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QuestionAnswered step-by-stepstudy investigated if psychotherapy combined with limited…study investigated if psychotherapy combined with limited administration of 3,4 Methylenedioxymethamphetamine (MDMA) can reduce symptoms of post-traumatic stress disorder. Severity of symptoms was measured via the CAPS-IV score with higher scores indicating more severe symptoms. Subjects recruited to the study were randomly allocated to one of the three dosage levels of MDMA (Low – 40 mg, Medium – 100 mg, High – 125 mg). The primary outcome was the reduction in CAPS-IV score at one month after the second treatment session. A secondary outcome was whether the subject experienced a drop of 20% or more in CAPS-IV score. BeforeCAPS-IV score before treatmentAfterCAPS-IV scores at the one month after the second treatment sessionChangeReduction in CAPS-IV scores (Before – After)DropWas a 20% reduction in CAPS-IV score achieved (TRUE or FALSE)DoseDosage of MDMA given (Low – 40 mg, Medium – 100 mg, High – 125 mg) Based on the information above, which of the following best describes the study? Randomised complete block design Randomised comparative double-blind experiment Randomised comparative experiment Observational studyQuestion 2The mean CAPS-IV score before treatment in the low dosage group is 63.1 77.0 77.6 78.2Question 3Researchers conduct a one-way ANOVA to determine if there is a difference in the mean reduction in CAPS-IV for the three dosage levels of MDMA. Which of the following describes the null hypothesis that is tested in a one-way ANOVA? The mean change in CAPS-IV score is zero for all dosage levels The mean change in CAPS-IV score is the same for all dosage levels The mean change in CAPS-IV score is different for at least one dosage level The mean change in CAPS-IV score is different for all dosage levelsQuestion 4What is the residual degrees of freedom in the one-way ANOVA to compare the mean reduction in CAPS-IV between the three dosage levels of MDMA? 2 47 51 53Question 5What is the Total Sum of Squares for this one-way ANOVA? 38.9 221.2 260.1 390.1Question 6Based on the F test for this one-way ANOVA, you can conclude there is no evidence to suggest that there is an effect of MDMA dosage on the mean change in patient’s CAPIS-IV score (p > 0.1) weak evidence to suggest that there is an effect of MDMA dosage on the mean change in patient’s CAPIS-IV score (p < 0.1) moderate evidence to suggest that there is an effect of MDMA dosage on the mean change in patient's CAPIS-IV score (p < 0.05) strong evidence to suggest that there is an effect of MDMA dosage on the mean change in patient's CAPIS-IV score (p < 0.01)Question 7What is the R2 value for this one-way ANOVA? 0.1497 0.2855 0.3869 0.8503Question 8Which of the following is NOT an assumption of this one-way ANOVA? There is a linear relationship between mean change in CAPS-IV score and dosage The changes in CAPS-IV score are independent The change in CAPS-IV score has a normal distribution The variability of the change in CAPS-IV scores does not depend on the dosageQuestion 9Which of the following would be most useful in assessing model assumptions? Scatterplot of the fitted values from the one-way ANOVA against dosage Normal probability plot of the changes in CAPS-IV score Scatterplot of Before against After CAPS-IV scores Normal probability plot of the residuals from the one-way ANOVAQuestion 10The researchers would like to understand which (if any) dosages of MDMA result in different mean changes in CAPS-IV score. Using Tukey's Honestly Significant Difference, the researchers are able to conclude that the mean changes in CAPS-IV score are different at the 5% (familywise) significance level for the following pairs of dosages: Only Low-High Medium-Low and Low-High Medium-High and Low-High Medium-Low, Medium-High and Low-HighQuestion 11A secondary outcome for the experiment was whether subjects experienced a 20% drop in CAPS-IV scores at one month after the second treatment session. How many subjects in the study experienced a 20% drop in their CAPS-IV score? 4 8 23 24Question 12What proportion of participants received a low dosage of MDMA and experienced a 20% drop in their CAPS-IV score? 0.093 0.217 0.241 0.278Question 13If there was no association between experiencing a 20% drop in CAPS-IV score and dosage level, what is the expected count for subjects in the low dosage group experiencing a 20% drop in CAPS-IV score? 7.67 9.00 11.74 15.00Question 14What is the value of the ?2 statistic used to test for an association between experiencing a 20% drop in CAPS-IV score and dosage level? 2.424 2.918 3.204 4.031Question 15What is the degrees of freedom for the ?2 test in Question 14? 2 3 5 6Question 16Based on this analysis, you can conclude that there is no evidence to suggest that there is an association between dosage level and experiencing a 20% drop in CAPS-IV score (p = 0.149) no evidence to suggest that there is an association between dosage level and experiencing a 20% drop in CAPS-IV score (p = 0.295) no evidence to suggest that there is an association between dosage level and experiencing a 20% drop in CAPS-IV score (p = 0.298) no evidence to suggest that there is an association between dosage level and experiencing a 20% drop in CAPS-IV score (p = 0.702)  Before After Change Drop Dose80 64 16 FALSE Medium79 60 19 TRUE Medium79 63 16 TRUE Medium80 63 17 TRUE Medium77 61 16 TRUE Medium74 59 15 TRUE Medium77 62 15 FALSE Medium80 65 15 FALSE Medium79 67 12 FALSE Medium79 63 16 TRUE Medium77 62 15 FALSE Medium81 68 13 FALSE Medium74 60 14 FALSE Medium78 62 16 TRUE Medium81 63 18 TRUE Medium81 64 17 TRUE Medium81 66 15 FALSE Medium78 63 15 FALSE Medium77 60 17 TRUE Low78 63 15 FALSE Low75 58 17 TRUE Low77 63 14 FALSE Low74 59 15 TRUE Low80 64 16 FALSE Low80 63 17 TRUE Low76 59 17 TRUE Low77 65 12 FALSE Low82 68 14 FALSE Low77 63 14 FALSE Low77 66 11 FALSE Low78 66 12 FALSE Low76 63 13 FALSE Low77 69 8 FALSE Low79 67 12 FALSE Low78 65 13 FALSE Low79 65 14 FALSE Low78 60 18 TRUE High80 63 17 TRUE High76 58 18 TRUE High78 64 14 FALSE High77 62 15 FALSE High80 64 16 FALSE High78 63 15 FALSE High79 68 11 FALSE High76 60 16 TRUE High79 62 17 TRUE High77 58 19 TRUE High80 65 15 FALSE High78 60 18 TRUE High76 61 15 FALSE High78 65 13 FALSE High81 64 17 TRUE High76 58 18 TRUE High83 69 14 FALSE High MathStatistics and ProbabilitySTAT 10Share Question

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Question Answered step-by-step You are the nurse working triage in the emergency department. Thisafternoon a woman brings in her father, K.B., a 72 year-old. The daughter reports that over the past several months she has noticed her father has progressively had problems with his mental capacity. These changes have developed gradually but seem to be getting worse. At times he is alert, and at other times he seems disoriented, depressed and tearful. He is forgetting thing and doing things out of the ordinary, such as placing the milk in the cupboard and sugar in the refrigerator. This morning he thought it was night time and wondered what his daughter was doing at his house. He could not pour his own coffee, and he seems to be getting more agitated. K.B. reports that he has been having memory problems for past year and at time has difficulty remembering the names of family members and friends.A review of his past medical history is significant for hypercholesterolemia and coronary artery disease. He had a myocardial infarction 5 years ago. K.B.'s vital signs today are all within normal limits.1. What are some cognate changes seen in a number of elderly patients?2. Age-related changes in the elderly may influence cognitive functions. Name and discuss one. Health Science Science Nursing Share QuestionEmailCopy link Comments (0)
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