Question Answered step-by-step Peer response help please? I will attach a copy my peers discussion.Instructions: PEERS POST:Acknowledge their posts, build upon what they have written, and conclude with thought to further the discussion.Disease Analysis JournalArticle 1: Race and gender variation is response to evoked inflammation.Pages Read: 10 Link:https://ccco.idm.oclc.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=87458539&site=eds-live&scope=siteKeywords: Gender, race, endotoxemia, biomarkers, cytokines, endotoxinsSummary:The focus of this research article was aimed to determine if there was a drastic difference in endotoxemia production between race and gender. Endotoxemia is the result of bacterial death. The toxins held within a bacterial cell are released into the host’s body and infiltrate the bloodstream. In doing so, the body’s immune response is activated in which inflammation could occur. Through the study, it was found African Americans developed a lower inflammatory response than European Americans did. While no definitive conclusion was made as to why, it could be presuming African Americans had a lower innate immunity response, which is the first line of defense of an individual’s immune system.I was drawn to this article due to the research they intended to find. As a nursing student, I am told to treat every patient as a unique individual and to keep an open mind if similar situations occur. While two patients may have the same diagnosis, their symptoms or physiological reactions could be drastically different. In a perfect world, the physiological response to foreign entities is to defend the body and activate the immune system accordingly.  This article shows there are differences in the level of activation of the innate immune response across race and gender, suggesting everyone could have varying responses to the same pathogen. Article 2: A Pediatric perspective on inflammation and oxidative stress in response to exercise.Pages Read: 10Link: https://ccco.idm.oclc.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=31358708&site=eds-live&scope=siteKeywords: Children, cytokines, exercise, oxidative stress, infants, exercise physique.Summary:Research on the relationship of the inflammatory response and oxidative stress on children who exercise is limited in the literature. The goal of this study was to show a link between exercise and tissue adaptations that lead to healthy growth in children by way of inflammatory or oxidative stress and increased growth factor production. When rigorous exercise induces oxidative stress, an immune response is activated. This induces inflammation which helps reduce the number of free radicals in the body caused by exercise. This relationship may benefit children in that exercise may provide an adaptation that is more efficient in clearing oxidative stress from the body, which in turn will benefit growth outcomes for those children.This article stood out from others due to its similarity to my previous studies for my undergraduate degree in Exercise Physiology. Although we did not focus on pediatrics, the adaptations the body underwent during exercise intrigued me to learn more. In learning the effects of exercise on an adolescent’s body in the prime phase of growth, it solidifies my opinion of the importance of having exercise incorporated more into a child’s life, whether it be elective or establish in grade school academics. Exercise in adolescence provides a positive deviation from the norm as it promotes growth and healthy well-being. This may play a role in decreasing childhood diseases by priming the immune system to better aide the development of the adolescent. Optional Choice #1: Fundamentals of Nursing – Chapter 12: Stress and AdaptationPages Read: 24Link: N/AKeyword(s): Inflammatory ResponseSummary:Utilizing a textbook from a previous semester, the inflammatory response can vary in location and severity but utilizes the same signs and symptoms. The inflammatory response can be triggered through a variety of methods, such as an autoimmune disorder, neoplastic growth, or physical trauma. The reaction; however, remains relatively the same for each type of cause. The inflammatory process undergoes three phases of response: Vascular response, cellular response, and exudate formation. During the vascular response, the blood vessels will constrict at the site of injury to limit blood loss from the body. The local cells will then release histamine, causing the surrounding vessels to dilate and allow blood flow carrying white blood cells (WBCs) to the area. This activates the cellular response where WBCs protect the body by eliminating foreign matter that has the potential to harm the system. Lastly, the exudate formation includes blood and cells filling the area to promote healing if a physical trauma caused the inflammatory response. This chapter was chosen due to the references to the body’s internal capabilities to stop a foreign body from invading. In cases involving cancer and autoimmune diseases, the inflammatory response is altered to promote the eradication of these diseases by prioritizing what is needed most during the reaction. When the inflammatory response is activated for a situation where bodily fluid is not being lost, there may not be an increase in fluid to the area, but there will be an abundance of WBCs. The primary conclusion of this chapter describes how the body will adjust to what is needed in an inflammatory response, rather than have a baseline standard for each situation.  Optional Choice #2: Fundamentals of Nursing – Chapter 23: Promoting Asepsis and Preventing InfectionPages Read: 27Link: N/AKeyword(s): ImmunitySummary:The use of immunizations against infectious diseases are driving factors in preventing worldwide outbreaks or exposures. Diseases such as measles, mumps, pertussis, polio, pneumonia, and influenzas all have vaccines to eliminate almost all risk of acquiring the disease. The higher the vaccination rate, the lower the risk of an outbreak in the community, which promotes a more optimistic future. However, if most of a population were to decline the vaccine, the risk for the disease (ex. Polio in Afghanistan & Saudi Arabia) could increase and affect the entire population. If a vaccine were to be deemed effective, at least 85% of the population would have to be immunized for the entire population to be protected. I selected this reading because immunity and vaccinations are a dominant topic in the modern world due to the Covid-19 pandemic. The constant debate between those who are for and against the vaccine continue to divide communities after the conception of the vaccine. While people are entitled to their respective beliefs and opinions, the consistent mutations and variants of the virus continue to manipulate what can be done in the world with vaccination rates below the required percentage to be considered effective. A conclusion I took from this reading is vaccines and immunity work only if most of the population are in favor of it. If the vaccine is met with resistance or pushback, the disease will continue to mutate and bypass the vaccines in place.   ReferencesFerguson, J. F., Patel, P. N., Shah, R. Y., Mulvey, C. K., Gadi, R., Nijjar, P. S., Usman, H. M., Mehta, N. N., Shah, R., Master, S. R., Propert, K. J., & Reilly, M. P. (2013). Race and gender variation in response to evoked inflammation. Journal of Translational Medicine, 11(1), 1-9. https://doi-org.ccco.idm.oclc.org/10.1186/1479-5876-11-63 Timmons, B. W., & Raha, S. (2008). A pediatric perspective on inflammation and oxidative stress in response to exercise. Applied Physiology, Nutrition & Metabolism, 33(2), 411-419. https://doi-org.ccco.idm.oclc.org/10.1139/H07-183 Wilkinson, J., Treas, L., Barnett, K., & Smith, M. (2019). Fundamentals of Nursing – Vol 1: Theory, Concepts, and Applications (4th ed.). F.A. Davis Company. Health Science Science Nursing BIO 216 Share QuestionEmailCopy link Comments (0)

Question Answered step-by-step Peer response help please? I will attach a copy my peers discussion.Instructions: PEERS POST:Acknowledge their posts, build upon what they have written, and conclude with thought to further the discussion.Disease Analysis JournalArticle 1: Race and gender variation is response to evoked inflammation.Pages Read: 10 Link:https://ccco.idm.oclc.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=87458539&site=eds-live&scope=siteKeywords: Gender, race, endotoxemia, biomarkers, cytokines, endotoxinsSummary:The focus of this research article was aimed to determine if there was a drastic difference in endotoxemia production between race and gender. Endotoxemia is the result of bacterial death. The toxins held within a bacterial cell are released into the host’s body and infiltrate the bloodstream. In doing so, the body’s immune response is activated in which inflammation could occur. Through the study, it was found African Americans developed a lower inflammatory response than European Americans did. While no definitive conclusion was made as to why, it could be presuming African Americans had a lower innate immunity response, which is the first line of defense of an individual’s immune system.I was drawn to this article due to the research they intended to find. As a nursing student, I am told to treat every patient as a unique individual and to keep an open mind if similar situations occur. While two patients may have the same diagnosis, their symptoms or physiological reactions could be drastically different. In a perfect world, the physiological response to foreign entities is to defend the body and activate the immune system accordingly.  This article shows there are differences in the level of activation of the innate immune response across race and gender, suggesting everyone could have varying responses to the same pathogen. Article 2: A Pediatric perspective on inflammation and oxidative stress in response to exercise.Pages Read: 10Link: https://ccco.idm.oclc.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=31358708&site=eds-live&scope=siteKeywords: Children, cytokines, exercise, oxidative stress, infants, exercise physique.Summary:Research on the relationship of the inflammatory response and oxidative stress on children who exercise is limited in the literature. The goal of this study was to show a link between exercise and tissue adaptations that lead to healthy growth in children by way of inflammatory or oxidative stress and increased growth factor production. When rigorous exercise induces oxidative stress, an immune response is activated. This induces inflammation which helps reduce the number of free radicals in the body caused by exercise. This relationship may benefit children in that exercise may provide an adaptation that is more efficient in clearing oxidative stress from the body, which in turn will benefit growth outcomes for those children.This article stood out from others due to its similarity to my previous studies for my undergraduate degree in Exercise Physiology. Although we did not focus on pediatrics, the adaptations the body underwent during exercise intrigued me to learn more. In learning the effects of exercise on an adolescent’s body in the prime phase of growth, it solidifies my opinion of the importance of having exercise incorporated more into a child’s life, whether it be elective or establish in grade school academics. Exercise in adolescence provides a positive deviation from the norm as it promotes growth and healthy well-being. This may play a role in decreasing childhood diseases by priming the immune system to better aide the development of the adolescent. Optional Choice #1: Fundamentals of Nursing – Chapter 12: Stress and AdaptationPages Read: 24Link: N/AKeyword(s): Inflammatory ResponseSummary:Utilizing a textbook from a previous semester, the inflammatory response can vary in location and severity but utilizes the same signs and symptoms. The inflammatory response can be triggered through a variety of methods, such as an autoimmune disorder, neoplastic growth, or physical trauma. The reaction; however, remains relatively the same for each type of cause. The inflammatory process undergoes three phases of response: Vascular response, cellular response, and exudate formation. During the vascular response, the blood vessels will constrict at the site of injury to limit blood loss from the body. The local cells will then release histamine, causing the surrounding vessels to dilate and allow blood flow carrying white blood cells (WBCs) to the area. This activates the cellular response where WBCs protect the body by eliminating foreign matter that has the potential to harm the system. Lastly, the exudate formation includes blood and cells filling the area to promote healing if a physical trauma caused the inflammatory response. This chapter was chosen due to the references to the body’s internal capabilities to stop a foreign body from invading. In cases involving cancer and autoimmune diseases, the inflammatory response is altered to promote the eradication of these diseases by prioritizing what is needed most during the reaction. When the inflammatory response is activated for a situation where bodily fluid is not being lost, there may not be an increase in fluid to the area, but there will be an abundance of WBCs. The primary conclusion of this chapter describes how the body will adjust to what is needed in an inflammatory response, rather than have a baseline standard for each situation.  Optional Choice #2: Fundamentals of Nursing – Chapter 23: Promoting Asepsis and Preventing InfectionPages Read: 27Link: N/AKeyword(s): ImmunitySummary:The use of immunizations against infectious diseases are driving factors in preventing worldwide outbreaks or exposures. Diseases such as measles, mumps, pertussis, polio, pneumonia, and influenzas all have vaccines to eliminate almost all risk of acquiring the disease. The higher the vaccination rate, the lower the risk of an outbreak in the community, which promotes a more optimistic future. However, if most of a population were to decline the vaccine, the risk for the disease (ex. Polio in Afghanistan & Saudi Arabia) could increase and affect the entire population. If a vaccine were to be deemed effective, at least 85% of the population would have to be immunized for the entire population to be protected. I selected this reading because immunity and vaccinations are a dominant topic in the modern world due to the Covid-19 pandemic. The constant debate between those who are for and against the vaccine continue to divide communities after the conception of the vaccine. While people are entitled to their respective beliefs and opinions, the consistent mutations and variants of the virus continue to manipulate what can be done in the world with vaccination rates below the required percentage to be considered effective. A conclusion I took from this reading is vaccines and immunity work only if most of the population are in favor of it. If the vaccine is met with resistance or pushback, the disease will continue to mutate and bypass the vaccines in place.   ReferencesFerguson, J. F., Patel, P. N., Shah, R. Y., Mulvey, C. K., Gadi, R., Nijjar, P. S., Usman, H. M., Mehta, N. N., Shah, R., Master, S. R., Propert, K. J., & Reilly, M. P. (2013). Race and gender variation in response to evoked inflammation. Journal of Translational Medicine, 11(1), 1-9. https://doi-org.ccco.idm.oclc.org/10.1186/1479-5876-11-63 Timmons, B. W., & Raha, S. (2008). A pediatric perspective on inflammation and oxidative stress in response to exercise. Applied Physiology, Nutrition & Metabolism, 33(2), 411-419. https://doi-org.ccco.idm.oclc.org/10.1139/H07-183 Wilkinson, J., Treas, L., Barnett, K., & Smith, M. (2019). Fundamentals of Nursing – Vol 1: Theory, Concepts, and Applications (4th ed.). F.A. Davis Company. Health Science Science Nursing BIO 216 Share QuestionEmailCopy link Comments (0)