Question 3 A pharmacist needs to prepare 50 capsules, each…
Question Question 3 A pharmacist needs to prepare 50 capsules, each… Question 3A pharmacist needs to prepare 50 capsules, each containing 4mg of estriol and 1mg of estradiol. A size 3 capsule is selected for this compounding. A capsule body is individually filled with each drug and lactose and the weights recorded as follows: Estriol 250mg, Estradiol 190mg and Lactose 320mg.Showing your work, calculate the amount of each drug and lactose needed to compound the capsules. [6 marks]Describe the method used to compound the capsules if the filling was done using a bench-scale capsule filling machine (PCCA – Jaansun 100 capsules). [2 marks]Explaining your answer, identify whether the filling using the capsule filling machine (in part b) is dependent or independent filling. [2 marks]Briefly discuss how the capsule shells used in this compounding are “hard” while the capsule shells in soft capsules are “soft” by describing the components in each type of capsules with one example for each component. [4 marks]The drug tipranavir is available in Australia under the name “Aptivus capsules” with a dose of 250 mg in each soft capsule. Answer the following questions for the product:Referring to Mims online (available in RMIT electronic library) outline the excipients used in the capsule matrix and their functions. [4 marks]Discuss the rationale for formulating the drug in this dosage form identifying why it has fast onset of action despite its poor water solubility. [2 marks] Health Science Science Nursing HEALTH PHAR1017 Share QuestionEmailCopy link Comments (0)
