Question 11 1. Is a local corticosteroid injection in the palm…

Question Answered step-by-step Question 11 1. Is a local corticosteroid injection in the palm… Question 111. Is a local corticosteroid injection in the palm effective in the case ofDupuytren’s contracture?2. Can Dupuytren’s contracture occur in early or well-controlleddiabetes, or is it more likely to occur in uncontrolled diabetes?Question 12Besides cirrhosis of the liver and diabetes mellitus (DM), what othercauses of Dupuytren’s contracture are there? What is thepathophysiology behind it?Question 13According to one of my lecturers, who is a very well-qualified doctorand orthopaedic specialist, there is an indirect connection betweenosteoarthritis and subclinical local infections (such as periodontalabscesses), changing the pH of bodily fluids. Can you explain thismechanism?Question 14What do you mean by saying that in nodal osteoarthritis each joint isaffected one at a time? Is it that each proximal interphalangeal (PIP) ordistal interphalangeal (DIP) joint is affected alone, or that at any one timePIP or DIP joints are affected together in one or both hands?Question 15What are the criteria for diagnosing osteoarthritis (OA) of the knee jointradiologically? Are changes to be expected with advancing age? To whatextent would I consider it significant in those below 50 years of age?Would you give me some X-ray examples if possible?Rheumatology and bone disease 1087Question 161. In a young patient with osteoarthritis, does long-term treatment withparacetamol (acetaminophen) 500 mg/day, rather than ibuprofen600 mg/day, lower the incidence of renal toxicity?2. How great is the risk of renal toxicity with both these treatments?Question 17In India, total knee replacements are being recommended for every caseof severe osteoarthritis, without considering factors such as age, weightor medical condition. What are the correct indications for surgery?Question 18Methotrexate therapy is usually begun in rheumatoid arthritis thatdoesn’t respond to NSAIDs plus 40-120 mg methylprednisolone depot.If a remission is then induced, how long should methotrexate therapybe continued? Will the patient (now in remission) be given maintenancetherapy?Question 19What is the dose and regimen for folinic acid rescue after methotrexate inrheumatoid arthritis?Question 201. What are the indicators of remission in rheumatoid arthritis? Is itnormalization of erythrocyte sedimentation rate (ESR) or clinicalimprovement?2. Does the rheumatoid factor disappear during a remission ofrheumatoid arthritis? Health Science Science Nursing Share QuestionEmailCopy link Comments (0)