Please provide answers to five questions below with their rationales including references
Question Answered step-by-step Please provide answers to five questions below with their rationales including references 1. A 65-year-old female presents to the clinic with a noticeable tremor in her left hand, bradykinesia, and loss of balance. She reports that three weeks ago she was seen by her neurologist, who put her on levodopa/carbidopa. She reports she took this medication for almost three weeks but stopped taking it two days ago after not noticing any improvement in her symptoms. Her reason for this visit was to request a medication that works better. What would be the most appropriate response from the provider in discussing the plan with the patient?A) A drug of the MAO-B class such as Rasagiline or Selegiline would probably work better for you. These drugs are often prescribed in newly diagnosed patients to reverse the neurodegeneration caused by the disorder.B) This medication is used to maintain functional ability; however, the full therapeutic response of levodopa may take several months to occur. I would like you to continue taking this medication for another three months and we will then re-evaluate any progress in your symptoms. Are you okay with this plan?C) I understand your concern. Three weeks should have been enough time to notice the beneficial effects of this drug. Let’s talk about other drug options that may suit you better.D) Your neurologist is the provider you should be speaking to regarding pharmacologic symptom management for your Parkinson’s disease. 2. Match the “boxed warnings” with the associated drug.A) CarbamazepineB) LamotrigineC) PhenytoinD) Valproate and Valproic Acid 1) Severe hypotension, cardiac dysrhythmias2) Fatal hepatic failure, fatal and rapidly progressing pancreatitis, highly teratogenic3) Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)4) Aplastic Anemia, Agranulocytosis, Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), Asian Ancestry 3. Which antiseizure drug poses a 4x higher risk (when compared with other antiseizure drugs) for a major congenital malformation?A) PrimidoneB) LamotrigineC) GabapentinD) Valproic acid 4. This drug class is used to terminate migraine headaches; however, they are contraindicated for patients with ischemic heart disease, prior MI, or uncontrolled hypertension. Additionally, no specific laboratory monitoring is necessary with this drug class.A) Ergot AlkaloidsB) TriptansC) NSAIDsD) Beta-Blockers 5. A 30-year-old female college student presents to the clinic complaining of unilateral throbbing head pain of moderate intensity. She reports her symptoms to worsen with light, noise, and motion. She reports episodes of the same symptoms occurring 15 times per month on average. Her only PMH reveals migraine headaches. She asks if there are any drugs available to prevent migraine attacks. As a provider, what drug would you recommend for initial therapy for migraine prophylaxis? Her vital signs are as follows: BP 128/90, HR 88, RR of 20, SpO2 of 98% on room air, 98.4 F temperature.A) Propranolol 80 mg/day PO given in divided dosesB) Sumatriptan 100 mg/day PO given in divided dosesC) Verapamil 240 mg/day PO given in divided dosesD) Topiramate 200 mg/day PO given in divided doses Health Science Science Nursing PHARM NR566 Share QuestionEmailCopy link Comments (0)
