Pharmacokinetic parameters for the medicines carbamazepine…
Question Answered step-by-step Pharmacokinetic parameters for the medicines carbamazepine… Pharmacokinetic parameters for the medicines carbamazepine (anti-convulsant),rifampicin and vancomycin (antibiotics) are compiled in the table below. PharmacokineticparametersCarbamezine Rifampicin VancomycinF (oral) 80 %100 %0% % excretedunchanged in urine 21595CL4 L/h10 L/h7 L/hVd (70 kg patient)105 L70 L35 Lt1/218 h5 h3.5 hAssuming first-order elimination kinetics, assign the properties listed below to thecorrect medicine (s):hepatic extraction ratio under 10% Carbamezine at least 95% cleared from the body one day after single dosereaching steady state takes a few days of repeated dosehighly affected by first pass metabolismsuitable for parenteral administration Biology Science Pharmacology ONPS 2032 Share QuestionEmailCopy link Comments (0)
